功能： Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity).
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Detected at the inner aspect of the plasma membrane in myotubes. .
组织表达： Widely expressed, with highest levels in heart and skeletal muscle, intermediate levels in placenta, liver and pancreas, and very low levels in brain, lung and kidney.
科研货号： PLA013834
PACSIN3 rabbit pAb
Catalog NoPLA013834
Product information
基因名称： PACSIN3
蛋白名称： Protein kinase C and casein kinase substrate in neurons protein 3 (Endophilin I) (SH3 domain-containing protein 6511)
功能： Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity).
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Detected at the inner aspect of the plasma membrane in myotubes. .
组织表达： Widely expressed, with highest levels in heart and skeletal muscle, intermediate levels in placenta, liver and pancreas, and very low levels in brain, lung and kidney.
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