功能： Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response . Involved in JNK signaling pathway (By similarity).
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle pole . Not detected in the cilium. Localized around the poles of the mitotic spindle from prophase to anaphase in mitotic cells. .
组织表达： Expressed in intestinal mucosa, where it is detected in epithelial cells, endothelial cells, smooth muscle cells and immune cells, such as lymphocytes (PubMed:22700971). Expressed in kidney (PubMed:28089251).
科研货号： PLA013833
MAPKBP1 rabbit pAb
Catalog NoPLA013833
Product information
基因名称： MAPKBP1 JNKBP1 KIAA0596
蛋白名称： Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1)
功能： Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response . Involved in JNK signaling pathway (By similarity).
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle pole . Not detected in the cilium. Localized around the poles of the mitotic spindle from prophase to anaphase in mitotic cells. .
组织表达： Expressed in intestinal mucosa, where it is detected in epithelial cells, endothelial cells, smooth muscle cells and immune cells, such as lymphocytes (PubMed:22700971). Expressed in kidney (PubMed:28089251).
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