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Toca 1 rabbit pAb
商品货号: PLA013697
适 应 性: 人,小鼠,大鼠
WB
¥600元
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MSDS
说明书
商品描述
  • 基因名称: FNBP1L C1orf39 TOCA1
  • 蛋白名称: Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1)
  • Human_gene_id: 54874
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54874
  • Human_swiss_prot_no: Q5T0N5
  • Human_swiss_link: https://www.uniprot.org/uniprot/Q5T0N5
  • Mouse_gene_id: 214459
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=214459
  • Mouse_swiss_prot_no: Q8K012
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q8K012/entry
  • Rat_gene_id: 310839
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=310839
  • Rat_swiss_prot_no: Q2HWF0
  • Rat_swiss_link: https://www.uniprot.org/uniprotkb/Q2HWF0/entry
  • 特异性: This antibody detects endogenous levels of Toca 1 at Human, Mouse,Rat
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 67kD
  • 功能: Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens.
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Cytoplasmic vesicle . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .
  • 科研货号: PLA013697
Toca 1 rabbit pAb
Catalog No PLA013697
Product information
  • 基因名称: FNBP1L C1orf39 TOCA1
  • 蛋白名称: Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1)
  • Human_gene_id: 54874
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54874
  • Human_swiss_prot_no: Q5T0N5
  • Human_swiss_link: https://www.uniprot.org/uniprot/Q5T0N5
  • Mouse_gene_id: 214459
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=214459
  • Mouse_swiss_prot_no: Q8K012
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q8K012/entry
  • Rat_gene_id: 310839
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=310839
  • Rat_swiss_prot_no: Q2HWF0
  • Rat_swiss_link: https://www.uniprot.org/uniprotkb/Q2HWF0/entry
  • 特异性: This antibody detects endogenous levels of Toca 1 at Human, Mouse,Rat
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 67kD
  • 功能: Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens.
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Cytoplasmic vesicle . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .
  • 科研货号: PLA013697
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    E-mail:service@uptbio.com
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