功能： Involved in cobalamin metabolism and trafficking . Plays a role in regulating the biosynthesis and the proportion of two coenzymes, methylcob(III)alamin (MeCbl) and 5'-deoxyadenosylcobalamin (AdoCbl) . Promotes oxidation of cob(II)alamin bound to MMACHC . The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Mitochondrion .
组织表达： Widely expressed at high levels.
科研货号： PLA013314
MMADHC rabbit pAb
Catalog NoPLA013314
Product information
基因名称： MMADHC C2orf25 CL25022 HSPC161 My011
蛋白名称： Methylmalonic aciduria and homocystinuria type D protein, mitochondrial
功能： Involved in cobalamin metabolism and trafficking . Plays a role in regulating the biosynthesis and the proportion of two coenzymes, methylcob(III)alamin (MeCbl) and 5'-deoxyadenosylcobalamin (AdoCbl) . Promotes oxidation of cob(II)alamin bound to MMACHC . The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine .
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