蛋白名称： Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (CHORD-containing protein 1) (CHP-1) (Protein morgana)
功能： Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2 . Proposed to act as co-chaperone for HSP90 . May play a role in the regulation of NOD1 via a HSP90 chaperone complex . In vitro, has intrinsic chaperone activity . This function may be achieved by inhibiting association of ROCK2 with NPM1 . Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling . Involved in stress response . Prevents tumorigenesis .
相关产品： RS0001,RS0002,YM3028,YM3029
组织表达： Underexpressed in many breast and lung cancers.
科研货号： PLA013253
CHORDC1 rabbit pAb
Catalog NoPLA013253
Product information
基因名称： CHORDC1 CHP1
蛋白名称： Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (CHORD-containing protein 1) (CHP-1) (Protein morgana)
功能： Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2 . Proposed to act as co-chaperone for HSP90 . May play a role in the regulation of NOD1 via a HSP90 chaperone complex . In vitro, has intrinsic chaperone activity . This function may be achieved by inhibiting association of ROCK2 with NPM1 . Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling . Involved in stress response . Prevents tumorigenesis .
相关产品： RS0001,RS0002,YM3028,YM3029
组织表达： Underexpressed in many breast and lung cancers.
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