功能： Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm . Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions (By similarity). Localizes mainly to the granular component, the region implicated in the later steps of rRNA processing and subunit assembly and export. .
科研货号： PLA013063
LAS1L rabbit pAb
Catalog NoPLA013063
Product information
基因名称： LAS1L MSTP060
蛋白名称： Ribosomal biogenesis protein LAS1L (Protein LAS1 homolog)
功能： Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm . Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions (By similarity). Localizes mainly to the granular component, the region implicated in the later steps of rRNA processing and subunit assembly and export. .
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