功能： Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity).
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Peroxisome .
科研货号： PLA012820
MARF1 rabbit pAb
Catalog NoPLA012820
Product information
基因名称： KIAA0430 LKAP MARF1
蛋白名称： Meiosis arrest female protein 1 (Limkain-b1)
功能： Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity).
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