功能： Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation . As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus, nucleoplasm . Localization at the nuclear pore complex requires NUP153 and TPR. .
科研货号： PLA012781
ENY2 rabbit pAb
Catalog NoPLA012781
Product information
基因名称： ENY2 DC6
蛋白名称： Enhancer of yellow 2 transcription factor homolog
功能： Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation . As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus, nucleoplasm . Localization at the nuclear pore complex requires NUP153 and TPR. .
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