功能： Acts as a transcriptional repressor . Represses cAMP-responsive element (CRE)-mediated transcriptional activation . In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis . Plays a key role in the transcriptional regulation of T lymphocyte development (By similarity).
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Nucleus, nucleoplasm . Localized in dot-like structures in the nucleus (PubMed:21706167). Colocalized with SMRT in nuclear bodies (PubMed:20797634). The sumoylated form is preferentially located in the nucleoplasm outside the nuclear bodies(PubMed:20797634). .
科研货号： PLA012669
ZBTB1 rabbit pAb
Catalog NoPLA012669
Product information
基因名称： ZBTB1 KIAA0997
蛋白名称： Zinc finger and BTB domain-containing protein 1
功能： Acts as a transcriptional repressor . Represses cAMP-responsive element (CRE)-mediated transcriptional activation . In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis . Plays a key role in the transcriptional regulation of T lymphocyte development (By similarity).
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Nucleus, nucleoplasm . Localized in dot-like structures in the nucleus (PubMed:21706167). Colocalized with SMRT in nuclear bodies (PubMed:20797634). The sumoylated form is preferentially located in the nucleoplasm outside the nuclear bodies(PubMed:20797634). .
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