蛋白名称： Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
功能： Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Bone marrow proteoglycan]: Secreted. The proform is secreted.; [Eosinophil granule major basic protein]: Cytoplasmic vesicle, secretory vesicle. The proform is secreted. The mature protein is found in the matrix of the eosinophil's large specific granule (crystalloid core).
组织表达： High levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon.
科研货号： PLA012528
PRG2 rabbit pAb
Catalog NoPLA012528
Product information
基因名称： PRG2 MBP
蛋白名称： Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
功能： Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Bone marrow proteoglycan]: Secreted. The proform is secreted.; [Eosinophil granule major basic protein]: Cytoplasmic vesicle, secretory vesicle. The proform is secreted. The mature protein is found in the matrix of the eosinophil's large specific granule (crystalloid core).
组织表达： High levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon.
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