功能： Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, synapse, postsynaptic cell membrane. Colocalized with MUSK at the neuromuscular junction. .
组织表达： Only expressed in melanomas. Weakly expressed in normal melanocytes and benign nevi. Highly expressed at the transition from radial growth phase to vertical growth phase and metastatic melanomas, when tumor cells acquire migratory competence and invasive potential.
科研货号： PLA012481
SHC4 rabbit pAb
Catalog NoPLA012481
Product information
基因名称： SHC4 SHCD UNQ6438/PRO21364
蛋白名称： SHC-transforming protein 4 (Rai-like protein) (RaLP) (SHC-transforming protein D) (hShcD) (Src homology 2 domain-containing-transforming protein C4) (SH2 domain protein C4)
功能： Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, synapse, postsynaptic cell membrane. Colocalized with MUSK at the neuromuscular junction. .
组织表达： Only expressed in melanomas. Weakly expressed in normal melanocytes and benign nevi. Highly expressed at the transition from radial growth phase to vertical growth phase and metastatic melanomas, when tumor cells acquire migratory competence and invasive potential.
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