功能： Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus .
科研货号： PLA012448
NIP30 rabbit pAb
Catalog NoPLA012448
Product information
基因名称： FAM192A C16orf94 NIP30 CDA018 CDA10
蛋白名称： Protein FAM192A (NEFA-interacting nuclear protein NIP30)
功能： Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus.
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