功能： Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs) . May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm, cytoskeleton, spindle . Subcellular localization is independent of the interaction with cullins. .
组织表达： Weakly expressed in testis, skin and immune tissues (thymus, spleen and lymph nodes).
科研货号： PLA012447
DCUN1D5 rabbit pAb
Catalog NoPLA012447
Product information
基因名称： DCUN1D5
蛋白名称： DCN1-like protein 5 (DCUN1 domain-containing protein 5) (Defective in cullin neddylation protein 1-like protein 5)
功能： Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs) . May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm, cytoskeleton, spindle . Subcellular localization is independent of the interaction with cullins. .
组织表达： Weakly expressed in testis, skin and immune tissues (thymus, spleen and lymph nodes).
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