功能： Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway . Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling . May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons (By similarity). Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation . May be involved in apoptosis .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform 1]: Cytoplasm.; [Isoform 2]: Mitochondrion. Cytoplasm. Expressed throughout the cytoplasm.; [Isoform 5]: Mitochondrion. Colocalizes with aggregated mitochondria.; Cell membrane ; Peripheral membrane protein .
组织表达： Detected in all tissues tested with highest levels of expression in brain and spleen.
科研货号： PLA012352
CAPRIN2 rabbit pAb
Catalog NoPLA012352
Product information
基因名称： CAPRIN2 C1QDC1 EEG1 KIAA1873 RNG140
蛋白名称： Caprin-2 (C1q domain-containing protein 1) (Cytoplasmic activation/proliferation-associated protein 2) (Gastric cancer multidrug resistance-associated protein) (Protein EEG-1) (RNA granule protein 140)
功能： Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway . Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling . May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons (By similarity). Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation . May be involved in apoptosis .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform 1]: Cytoplasm.; [Isoform 2]: Mitochondrion. Cytoplasm. Expressed throughout the cytoplasm.; [Isoform 5]: Mitochondrion. Colocalizes with aggregated mitochondria.; Cell membrane ; Peripheral membrane protein .
组织表达： Detected in all tissues tested with highest levels of expression in brain and spleen.
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