HOP2 rabbit pAb

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HOP2 rabbit pAb

商品货号： PLA012166

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： PSMC3IP HOP2 TBPIP
蛋白名称： Homologous-pairing protein 2 homolog (Nuclear receptor coactivator GT198) (PSMC3-interacting protein) (Proteasome 26S ATPase subunit 3-interacting protein) (Tat-binding protein 1-interacting protein) (TBP-1-interacting protein)
Human_gene_id： 29893
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29893
Human_swiss_prot_no： Q9P2W1
Human_swiss_link： https://www.uniprot.org/uniprot/Q9P2W1
Mouse_gene_id： 19183
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19183
Mouse_swiss_prot_no： O35047
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O35047/entry
Rat_gene_id： 140938
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=140938
Rat_swiss_prot_no： Q91ZY6
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q91ZY6/entry
特异性： This antibody detects endogenous levels of HOP2 at Human, Mouse,Rat
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
分子量： 24kD
功能： Plays an important role in meiotic recombination. Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. May inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3. Acts as a tissue specific coactivator of hormone-dependent transcription mediated by nuclear receptors.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus .
组织表达： Highly expressed in testis and colon.
科研货号： PLA012166

HOP2 rabbit pAb

Catalog No PLA012166

Product information

基因名称： PSMC3IP HOP2 TBPIP
蛋白名称： Homologous-pairing protein 2 homolog (Nuclear receptor coactivator GT198) (PSMC3-interacting protein) (Proteasome 26S ATPase subunit 3-interacting protein) (Tat-binding protein 1-interacting protein) (TBP-1-interacting protein)
Human_gene_id： 29893
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29893
Human_swiss_prot_no： Q9P2W1
Human_swiss_link： https://www.uniprot.org/uniprot/Q9P2W1
Mouse_gene_id： 19183
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19183
Mouse_swiss_prot_no： O35047
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O35047/entry
Rat_gene_id： 140938
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=140938
Rat_swiss_prot_no： Q91ZY6
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q91ZY6/entry
特异性： This antibody detects endogenous levels of HOP2 at Human, Mouse,Rat
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
分子量： 24kD
功能： Plays an important role in meiotic recombination. Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. May inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3. Acts as a tissue specific coactivator of hormone-dependent transcription mediated by nuclear receptors.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus .
组织表达： Highly expressed in testis and colon.
科研货号： PLA012166

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