功能： Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted . Endoplasmic reticulum-Golgi intermediate compartment . Endoplasmic reticulum . Golgi apparatus . The C-terminal RTEL motif may provide retention in the endoplasmic reticulum. .
组织表达： Expressed in eosinophils (at protein level) (PubMed:29954947). Expressed in bone marrow cells (PubMed:25581518). Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties (PubMed:17362502).
功能： Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted . Endoplasmic reticulum-Golgi intermediate compartment . Endoplasmic reticulum . Golgi apparatus . The C-terminal RTEL motif may provide retention in the endoplasmic reticulum. .
组织表达： Expressed in eosinophils (at protein level) (PubMed:29954947). Expressed in bone marrow cells (PubMed:25581518). Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties (PubMed:17362502).
在线咨询
湘公网安备