功能： Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus . Nucleus matrix . Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation. .
组织表达： Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.
科研货号： PLA012117
SORBS1 rabbit pAb
Catalog NoPLA012117
Product information
基因名称： SORBS1 KIAA0894 KIAA1296 SH3D5
蛋白名称： Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
功能： Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus . Nucleus matrix . Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation. .
组织表达： Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.
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