功能： Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum . Dispensable for SPC enzymatic activity (By similarity). ; (Microbial infection) Required for the post-translational processing of proteins involved in virion assembly and secretion from flaviviruses such as West Nile virus (WNV), Japanese encephalitis virus (JEV), Dengue virus type 2 (DENV-2), Yellow Fever virus (YFV), Zika virus (ZIKV) and hepatitis C virus (HCV) . Plays a key role in the post-translational processing of flaviviral structural proteins prM, E, and NS1 . In HCV, it is involved in virion assembly where it promotes the interaction between HCV virus proteins NS2 and E2 .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein .
科研货号： PLA012093
SPCS1 rabbit pAb
Catalog NoPLA012093
Product information
基因名称： SPCS1 SPC12 HSPC033
蛋白名称： Signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit)
功能： Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum . Dispensable for SPC enzymatic activity (By similarity). ; (Microbial infection) Required for the post-translational processing of proteins involved in virion assembly and secretion from flaviviruses such as West Nile virus (WNV), Japanese encephalitis virus (JEV), Dengue virus type 2 (DENV-2), Yellow Fever virus (YFV), Zika virus (ZIKV) and hepatitis C virus (HCV) . Plays a key role in the post-translational processing of flaviviral structural proteins prM, E, and NS1 . In HCV, it is involved in virion assembly where it promotes the interaction between HCV virus proteins NS2 and E2 .
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein .
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