功能： May regulate actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F-actin. The localized formation of TARA and TRIO complexes coordinates the amount of F-actin present in stress fibers. May also serve as a linker protein to recruit proteins required for F-actin formation and turnover.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm, cytoskeleton . Localized to F-actin in a periodic pattern. .; [Isoform 1]: Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Midbody . Centrosomal localization occurs upon phosphorylation by PLK1 at Thr-457 and lasts from prophase to anaphase. At telophase, relocalizes to midbody. .
组织表达： Widely expressed. Highly expressed in heart and placenta. Isoform 3 is expressed in fetal brain, retina and cochlea but is not detectable in the other tissues.
科研货号： PLA012053
TRIOBP rabbit pAb
Catalog NoPLA012053
Product information
基因名称： TRIOBP KIAA1662 TARA HRIHFB2122
蛋白名称： TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin)
功能： May regulate actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F-actin. The localized formation of TARA and TRIO complexes coordinates the amount of F-actin present in stress fibers. May also serve as a linker protein to recruit proteins required for F-actin formation and turnover.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm, cytoskeleton . Localized to F-actin in a periodic pattern. .; [Isoform 1]: Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Midbody . Centrosomal localization occurs upon phosphorylation by PLK1 at Thr-457 and lasts from prophase to anaphase. At telophase, relocalizes to midbody. .
组织表达： Widely expressed. Highly expressed in heart and placenta. Isoform 3 is expressed in fetal brain, retina and cochlea but is not detectable in the other tissues.
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