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CNOT3 rabbit pAb
商品货号: PLA011959
适 应 性: 人,小鼠
WB
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: CNOT3 KIAA0691 LENG2 NOT3
  • 蛋白名称: CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2)
  • Human_gene_id: 4849
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4849
  • Human_swiss_prot_no: O75175
  • Human_swiss_link: https://www.uniprot.org/uniprot/O75175
  • Mouse_gene_id: 232791
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=232791
  • Mouse_swiss_prot_no: Q8K0V4
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q8K0V4/entry
  • 特异性: This antibody detects endogenous levels of CNOT3 at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 83kD
  • 功能: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity.
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Nucleus . Cytoplasm, P-body . NANOS2 promotes its localization to P-body. .
  • 组织表达: Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes.
  • 科研货号: PLA011959
CNOT3 rabbit pAb
Catalog No PLA011959
Product information
  • 基因名称: CNOT3 KIAA0691 LENG2 NOT3
  • 蛋白名称: CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2)
  • Human_gene_id: 4849
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4849
  • Human_swiss_prot_no: O75175
  • Human_swiss_link: https://www.uniprot.org/uniprot/O75175
  • Mouse_gene_id: 232791
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=232791
  • Mouse_swiss_prot_no: Q8K0V4
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q8K0V4/entry
  • 特异性: This antibody detects endogenous levels of CNOT3 at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 83kD
  • 功能: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity.
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Nucleus . Cytoplasm, P-body . NANOS2 promotes its localization to P-body. .
  • 组织表达: Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes.
  • 科研货号: PLA011959
  • Hunan UPT Biotechnology Co.,Ltd
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    E-mail:service@uptbio.com
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