功能： Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform Alpha]: Lateral cell membrane; Lipid-anchor. Targeted predominantly to the lateral membrane.; [Isoform Beta]: Apical cell membrane; Lipid-anchor. Targeted predominantly to the apical membrane.
组织表达： Expressed in brain, heart, lung, pancreas and skeletal muscle.
科研货号： PLA011945
AKAP7 rabbit pAb
Catalog NoPLA011945
Product information
基因名称： AKAP7 AKAP15 AKAP18
蛋白名称： A-kinase anchor protein 7 isoforms alpha and beta (AKAP-7 isoforms alpha and beta) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoforms alpha/beta) (PRKA7 isoforms alpha/beta)
功能： Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform Alpha]: Lateral cell membrane; Lipid-anchor. Targeted predominantly to the lateral membrane.; [Isoform Beta]: Apical cell membrane; Lipid-anchor. Targeted predominantly to the apical membrane.
组织表达： Expressed in brain, heart, lung, pancreas and skeletal muscle.
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