功能： Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus membrane . Cytoplasm, cytosol . A smaller amount is detected in the cytosol.
组织表达： Expressed at highest levels in placenta and at lower levels in lung, liver, kidney and pancreas. Expressed in thalamus, hippocampus, cerebral cortex, and cerebellum (in neurons rather than glia).
科研货号： PLA011856
PRICKLE1 rabbit pAb
Catalog NoPLA011856
Product information
基因名称： PRICKLE1 RILP
蛋白名称： Prickle-like protein 1 (REST/NRSF-interacting LIM domain protein 1)
功能： Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus membrane . Cytoplasm, cytosol . A smaller amount is detected in the cytosol.
组织表达： Expressed at highest levels in placenta and at lower levels in lung, liver, kidney and pancreas. Expressed in thalamus, hippocampus, cerebral cortex, and cerebellum (in neurons rather than glia).
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