功能： Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum lumen .
科研货号： PLA011799
TXNDC4 rabbit pAb
Catalog NoPLA011799
Product information
基因名称： ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075
蛋白名称： Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)
功能： Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum.
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