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TRIM32 rabbit pAb
商品货号: PLA011561
适 应 性: 人,小鼠
WB
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: TRIM32 HT2A
  • 蛋白名称: E3 ubiquitin-protein ligase TRIM32 (EC 6.3.2.-) (72 kDa Tat-interacting protein) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)
  • Human_gene_id: 22954
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22954
  • Human_swiss_prot_no: Q13049
  • Human_swiss_link: https://www.uniprot.org/uniprot/Q13049
  • Mouse_gene_id: 69807
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69807
  • Mouse_swiss_prot_no: Q8CH72
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q8CH72/entry
  • 特异性: This antibody detects endogenous levels of TRIM32 at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 72kD
  • 功能: Has an E3 ubiquitin ligase activity . Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation . May ubiquitinate BBS2 . Ubiquitinates PIAS4/PIASY and promotes its degradation in keratinocytes treated with UVB and TNF-alpha (By similarity). Also acts as a regulator of autophagy by mediating formation of unanchored 'Lys-63'-linked polyubiquitin chains that activate ULK1: interaction with AMBRA1 is required for ULK1 activation . ; (Microbial infection) May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo . Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo .
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Localized in cytoplasmic bodies, often located around the nucleus. .
  • 组织表达: Spleen, thymus, prostate, testis, ovary, intestine, colon and skeletal muscle.
  • 科研货号: PLA011561
TRIM32 rabbit pAb
Catalog No PLA011561
Product information
  • 基因名称: TRIM32 HT2A
  • 蛋白名称: E3 ubiquitin-protein ligase TRIM32 (EC 6.3.2.-) (72 kDa Tat-interacting protein) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)
  • Human_gene_id: 22954
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22954
  • Human_swiss_prot_no: Q13049
  • Human_swiss_link: https://www.uniprot.org/uniprot/Q13049
  • Mouse_gene_id: 69807
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69807
  • Mouse_swiss_prot_no: Q8CH72
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q8CH72/entry
  • 特异性: This antibody detects endogenous levels of TRIM32 at Human, Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 72kD
  • 功能: Has an E3 ubiquitin ligase activity . Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation . May ubiquitinate BBS2 . Ubiquitinates PIAS4/PIASY and promotes its degradation in keratinocytes treated with UVB and TNF-alpha (By similarity). Also acts as a regulator of autophagy by mediating formation of unanchored 'Lys-63'-linked polyubiquitin chains that activate ULK1: interaction with AMBRA1 is required for ULK1 activation . ; (Microbial infection) May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo . Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo .
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Localized in cytoplasmic bodies, often located around the nucleus. .
  • 组织表达: Spleen, thymus, prostate, testis, ovary, intestine, colon and skeletal muscle.
  • 科研货号: PLA011561
  • Hunan UPT Biotechnology Co.,Ltd
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    E-mail:service@uptbio.com
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