功能： Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. ; [Isoform 2]: May have a higher activity than isoform 1.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Basolateral cell membrane ; Multi-pass membrane protein .
组织表达： Isoform 1 is expressed in pancreas and to a lower extent in heart, skeletal muscle, liver, parotid salivary glands, prostate, colon, stomach, thyroid, brain and spinal chord. Corneal endothelium cells express only isoform 1 (at protein level). Isoform 2 is specifically expressed in kidney at the level of proximal tubules.
科研货号： PLA011455
SLC4A4 rabbit pAb
Catalog NoPLA011455
Product information
基因名称： SLC4A4 NBC NBC1 NBCE1
蛋白名称： Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1)
功能： Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. ; [Isoform 2]: May have a higher activity than isoform 1.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Basolateral cell membrane ; Multi-pass membrane protein .
组织表达： Isoform 1 is expressed in pancreas and to a lower extent in heart, skeletal muscle, liver, parotid salivary glands, prostate, colon, stomach, thyroid, brain and spinal chord. Corneal endothelium cells express only isoform 1 (at protein level). Isoform 2 is specifically expressed in kidney at the level of proximal tubules.
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