功能： May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytosol . Cell projection, dendrite . Cell projection, lamellipodium . Associated with RNA granules. At the leading edge of migrating fibroblasts, colocalizes with DDX3X (PubMed:28733330). .
组织表达： Ubiquitous.
tag： hot
科研货号： PLA011398
CAPRIN1 rabbit pAb
Catalog NoPLA011398
Product information
基因名称： CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105
蛋白名称： Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105)
功能： May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytosol . Cell projection, dendrite . Cell projection, lamellipodium . Associated with RNA granules. At the leading edge of migrating fibroblasts, colocalizes with DDX3X (PubMed:28733330). .
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