其他名称： GRB2-associated-binding protein 1 (GRB2-associated binder 1;Growth factor receptor bound protein 2-associated protein 1)
实测条带： 76kD
信号通路： ErbB_HER;Neurotrophin;Renal cell carcinoma;
功能： function:Probably involved in EGF and insulin receptor signaling.,PTM:Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.,similarity:Belongs to the GAB family.,similarity:Contains 1 PH domain.,subunit:Interacts with GRB2 and with other SH2-containing proteins. Interacts with phosphorylated LAT2.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： cytosol,
组织表达： Testis,Whole embryo,
科研货号： PLA011297
Gab1 Rabbit Polyclonal Antibody
Catalog NoPLA011297
Product information
基因名称： GAB1
蛋白名称： GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
其他名称： GRB2-associated-binding protein 1 (GRB2-associated binder 1;Growth factor receptor bound protein 2-associated protein 1)
实测条带： 76kD
信号通路： ErbB_HER;Neurotrophin;Renal cell carcinoma;
功能： function:Probably involved in EGF and insulin receptor signaling.,PTM:Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.,similarity:Belongs to the GAB family.,similarity:Contains 1 PH domain.,subunit:Interacts with GRB2 and with other SH2-containing proteins. Interacts with phosphorylated LAT2.,
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