HIF-1β Polyclonal Antibody

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商品货号： PLA011278

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： ARNT
蛋白名称： Aryl hydrocarbon receptor nuclear translocator
Human_gene_id： 405
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=405
Human_swiss_prot_no： P27540
Human_swiss_link： http://www.uniprot.org/uniprotkb/P27540/entry
Mouse_swiss_prot_no： P53762
Mouse_swiss_link： http://www.uniprot.org/uniprot/P53762
Rat_swiss_prot_no： P41739
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P41739
特异性： The antibody detects endogenous HIF-1β protein.
组成： PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:1000-2000 IHC 1:200-500. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta
实测条带： 87kD
信号通路： Pathways in cancer;Renal cell carcinoma;
功能： function:Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,similarity:Contains 1 PAC (PAS-associated C-terminal) domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with AHR, AHRR, HIF1A and EPAS1/HIF2A as well as with other bHLH proteins. Interacts with TACC3 (By similarity). Interacts with NOCA7.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus.
组织表达： Aorta endothelial cell,Brain,Kidney,Thalamus,Uterus,
科研货号： PLA011278

HIF-1β Polyclonal Antibody

Catalog No PLA011278

Product information

基因名称： ARNT
蛋白名称： Aryl hydrocarbon receptor nuclear translocator
Human_gene_id： 405
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=405
Human_swiss_prot_no： P27540
Human_swiss_link： http://www.uniprot.org/uniprotkb/P27540/entry
Mouse_swiss_prot_no： P53762
Mouse_swiss_link： http://www.uniprot.org/uniprot/P53762
Rat_swiss_prot_no： P41739
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P41739
特异性： The antibody detects endogenous HIF-1β protein.
组成： PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:1000-2000 IHC 1:200-500. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta
实测条带： 87kD
信号通路： Pathways in cancer;Renal cell carcinoma;
功能： function:Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,similarity:Contains 1 PAC (PAS-associated C-terminal) domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with AHR, AHRR, HIF1A and EPAS1/HIF2A as well as with other bHLH proteins. Interacts with TACC3 (By similarity). Interacts with NOCA7.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus.
组织表达： Aorta endothelial cell,Brain,Kidney,Thalamus,Uterus,
科研货号： PLA011278

Hunan UPT Biotechnology Co.,Ltd

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