其他名称: Small conductance calcium-activated potassium channel protein 3 (SK3;SKCa 3;SKCa3;KCa2.3)
实测条带: 82kD
功能: function:Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.,polymorphism:The second poly-Gln region of KCNN3 is highly polymorphic and the number of Gln varies from 12 to 28 in the population.,similarity:Belongs to the potassium channel KCNN family.,subunit:Heterooligomer. The complex is composed of 4 channel subunits each of which binds to a calmodulin subunit which regulates the channel activity through calcium-binding.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Membrane; Multi-pass membrane protein.
组织表达: Atrium,Lymph,Non-pregnant myometrium,
科研货号: PLA011268
KCNN3 (SK3) Polyclonal Antibody
Catalog NoPLA011268
Product information
基因名称: KCNN3
蛋白名称: Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa 3) (SKCa3) (KCa2.3)
其他名称: Small conductance calcium-activated potassium channel protein 3 (SK3;SKCa 3;SKCa3;KCa2.3)
实测条带: 82kD
功能: function:Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.,polymorphism:The second poly-Gln region of KCNN3 is highly polymorphic and the number of Gln varies from 12 to 28 in the population.,similarity:Belongs to the potassium channel KCNN family.,subunit:Heterooligomer. The complex is composed of 4 channel subunits each of which binds to a calmodulin subunit which regulates the channel activity through calcium-binding.,