功能： disease:In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.,domain:An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes.,function:Implicated in endocytosis. May recruit other proteins to membranes with high curvature.,similarity:Belongs to the endophilin family.,similarity:Contains 1 BAR domain.,similarity:Contains 1 SH3 domain.,subcellular location:Associated with postsynaptic endosomes in hippocampal neurons.,subunit:Interacts with ARC (By similarity). Interacts with SYNJ1 and DNM1. Interacts with PDCD6IP.,tissue specificity:Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Early endosome membrane ; Peripheral membrane protein . Cell projection, podosome . Associated with postsynaptic endosomes in hippocampal neurons. .
组织表达： Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus.
功能： disease:In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.,domain:An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes.,function:Implicated in endocytosis. May recruit other proteins to membranes with high curvature.,similarity:Belongs to the endophilin family.,similarity:Contains 1 BAR domain.,similarity:Contains 1 SH3 domain.,subcellular location:Associated with postsynaptic endosomes in hippocampal neurons.,subunit:Interacts with ARC (By similarity). Interacts with SYNJ1 and DNM1. Interacts with PDCD6IP.,tissue specificity:Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Early endosome membrane ; Peripheral membrane protein . Cell projection, podosome . Associated with postsynaptic endosomes in hippocampal neurons. .
组织表达： Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus.
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