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TRPC6 rabbit pAb
商品货号: PLA009873
适 应 性: 人,小鼠
WB
¥600元
规格:
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MSDS
说明书
商品描述
  • 发货日期: 7
  • 基因名称: TRPC6 TRP6
  • 蛋白名称: TRPC6
  • Human_gene_id: 7225
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7225
  • Human_swiss_prot_no: Q9Y210
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/Q9Y210/entry
  • Mouse_gene_id: 22068
  • Mouse_gene_link: https://www.uniprot.org/uniprot/22068
  • Mouse_swiss_prot_no: Q61143
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q61143
  • 特异性: This antibody detects endogenous levels of TRPC6 at Human/Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 102kD
  • 功能: disease:Defects in TRPC6 are the cause of focal segmental glomerulosclerosis 2 (FSGS2) [MIM:603965]. FSGS2 is an autosomal dominant disease characterized by increased urinary protein excretion (proteinuria) and decreasing kidney function (nephrotic syndrome). Renal insufficiency often progresses to end-stage renal disease (ESRD) (also known as end-stage renal failure), a highly morbid state requiring either dialysis therapy or kidney transplantation.,function:Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.,similarity:Belongs to the transient receptor family. STrpC subfamily.,similarity:Contains 4 ANK repeats.,subunit:Interacts with MX1 and RNF24.,tissue specificity:Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane ; Multi-pass membrane protein .
  • 组织表达: Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm.
  • 科研货号: PLA009873
TRPC6 rabbit pAb
Catalog No PLA009873
Product information
  • 发货日期: 7
  • 基因名称: TRPC6 TRP6
  • 蛋白名称: TRPC6
  • Human_gene_id: 7225
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7225
  • Human_swiss_prot_no: Q9Y210
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/Q9Y210/entry
  • Mouse_gene_id: 22068
  • Mouse_gene_link: https://www.uniprot.org/uniprot/22068
  • Mouse_swiss_prot_no: Q61143
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q61143
  • 特异性: This antibody detects endogenous levels of TRPC6 at Human/Mouse
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 102kD
  • 功能: disease:Defects in TRPC6 are the cause of focal segmental glomerulosclerosis 2 (FSGS2) [MIM:603965]. FSGS2 is an autosomal dominant disease characterized by increased urinary protein excretion (proteinuria) and decreasing kidney function (nephrotic syndrome). Renal insufficiency often progresses to end-stage renal disease (ESRD) (also known as end-stage renal failure), a highly morbid state requiring either dialysis therapy or kidney transplantation.,function:Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.,similarity:Belongs to the transient receptor family. STrpC subfamily.,similarity:Contains 4 ANK repeats.,subunit:Interacts with MX1 and RNF24.,tissue specificity:Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane ; Multi-pass membrane protein .
  • 组织表达: Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm.
  • 科研货号: PLA009873
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    E-mail:service@uptbio.com
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