功能： disease:Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS) [MIM:208050]. ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.,function:Facilitative glucose transporter.,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,tissue specificity:Widely expressed; highest levels in liver and pancreas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endomembrane system ; Multi-pass membrane protein . Cytoplasm, perinuclear region .
组织表达： Widely expressed; highest levels in liver and pancreas.
功能： disease:Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS) [MIM:208050]. ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.,function:Facilitative glucose transporter.,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,tissue specificity:Widely expressed; highest levels in liver and pancreas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endomembrane system ; Multi-pass membrane protein . Cytoplasm, perinuclear region .
组织表达： Widely expressed; highest levels in liver and pancreas.
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