功能： disease:Defects in ROM1 may cause retinitis pigmentosa (RP) [MIM:268000]; when associated with defects in PRPH2.,function:May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis.,online information:Retina International's Scientific Newsletter,similarity:Belongs to the PRPH2/ROM1 family.,subunit:Homodimer; disulfide-linked. Probably forms a complex with a PRPH2 homodimer. Other proteins could associate with this complex in rods.,tissue specificity:Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Photoreceptor inner segment membrane ; Multi-pass membrane protein . Photoreceptor outer segment membrane ; Multi-pass membrane protein .
组织表达： Retina photoreceptors (at protein level) (PubMed:1610568, PubMed:8504299). In rim region of ROS disks (PubMed:1610568).
功能： disease:Defects in ROM1 may cause retinitis pigmentosa (RP) [MIM:268000]; when associated with defects in PRPH2.,function:May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis.,online information:Retina International's Scientific Newsletter,similarity:Belongs to the PRPH2/ROM1 family.,subunit:Homodimer; disulfide-linked. Probably forms a complex with a PRPH2 homodimer. Other proteins could associate with this complex in rods.,tissue specificity:Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Photoreceptor inner segment membrane ; Multi-pass membrane protein . Photoreceptor outer segment membrane ; Multi-pass membrane protein .
组织表达： Retina photoreceptors (at protein level) (PubMed:1610568, PubMed:8504299). In rim region of ROS disks (PubMed:1610568).
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