功能： function:Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition.,miscellaneous:Its expression in hepatoma cell lines may lead to increase DNA synthesis and thereby participate to cell proliferation.,pathway:Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.,similarity:Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.,subunit:Heterotetramer composed of 2 catalytic alpha subunits (alpha and alpha') (MAT2A) and 1 copy of beta subunit (MAT2B).,tissue specificity:Widely expressed.,
功能： function:Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition.,miscellaneous:Its expression in hepatoma cell lines may lead to increase DNA synthesis and thereby participate to cell proliferation.,pathway:Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.,similarity:Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.,subunit:Heterotetramer composed of 2 catalytic alpha subunits (alpha and alpha') (MAT2A) and 1 copy of beta subunit (MAT2B).,tissue specificity:Widely expressed.,
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