其他名称： Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4)
实测条带： 105kD
功能： function:Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS).,similarity:Contains 1 CARD domain.,similarity:Contains 1 NACHT domain.,similarity:Contains 9 LRR (leucine-rich) repeats.,subunit:Self-associates. Binds to caspase-9 and RIPK2 by CARD-CARD interaction.,tissue specificity:Highly expressed in adult heart, skeletal muscle, pancreas, spleen and ovary. Also detected in placenta, lung, liver, kidney, thymus, testis, small intestine and colon.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm. Cell membrane . Apical cell membrane. Basolateral cell membrane. Detected in the cytoplasm and at the cell membrane. Following bacterial infection, localizes to bacterial entry sites in the cell membrane. Recruited to the basolateral and apical membranes in polarized epithelial cells.
组织表达： Highly expressed in adult heart, skeletal muscle, pancreas, spleen and ovary. Also detected in placenta, lung, liver, kidney, thymus, testis, small intestine and colon.
其他名称： Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4)
实测条带： 105kD
功能： function:Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS).,similarity:Contains 1 CARD domain.,similarity:Contains 1 NACHT domain.,similarity:Contains 9 LRR (leucine-rich) repeats.,subunit:Self-associates. Binds to caspase-9 and RIPK2 by CARD-CARD interaction.,tissue specificity:Highly expressed in adult heart, skeletal muscle, pancreas, spleen and ovary. Also detected in placenta, lung, liver, kidney, thymus, testis, small intestine and colon.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm. Cell membrane . Apical cell membrane. Basolateral cell membrane. Detected in the cytoplasm and at the cell membrane. Following bacterial infection, localizes to bacterial entry sites in the cell membrane. Recruited to the basolateral and apical membranes in polarized epithelial cells.
组织表达： Highly expressed in adult heart, skeletal muscle, pancreas, spleen and ovary. Also detected in placenta, lung, liver, kidney, thymus, testis, small intestine and colon.
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