功能： function:May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translation N-terminally extended.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 G-patch domain.,similarity:Contains 1 RanBP2-type zinc finger.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subcellular location:In the extranucleolar nucleoplasm constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner. Upon globally reducing RNA polymerase II transcription, the nuclear bodies enlarge and decrease in number. They occur closely adjacent to nuclear speckles or IGCs (interchromatin granule clusters) but coincide with TIDRs (transcription-inactivation-dependent RNA domains).,subunit:Associates with the spliceosome. Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . In the extranucleolar nucleoplasm constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner. Upon globally reducing RNA polymerase II transcription, the nuclear bodies enlarge and decrease in number. They occur closely adjacent to nuclear speckles or IGCs (interchromatin granule clusters) but coincide with TIDRs (transcription-inactivation-dependent RNA domains).
组织表达： Bone marrow,Brain,Colon,Epithelium,Fetal brain,Human endometrium,Liver,Lung
科研货号： PLA008814
RBM10 Polyclonal Antibody
Catalog NoPLA008814
Product information
基因名称： RBM10 DXS8237E GPATC9 GPATCH9 KIAA0122
蛋白名称： RNA-binding protein 10 (G patch domain-containing protein 9) (RNA-binding motif protein 10) (RNA-binding protein S1-1) (S1-1)
功能： function:May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translation N-terminally extended.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 G-patch domain.,similarity:Contains 1 RanBP2-type zinc finger.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subcellular location:In the extranucleolar nucleoplasm constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner. Upon globally reducing RNA polymerase II transcription, the nuclear bodies enlarge and decrease in number. They occur closely adjacent to nuclear speckles or IGCs (interchromatin granule clusters) but coincide with TIDRs (transcription-inactivation-dependent RNA domains).,subunit:Associates with the spliceosome. Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . In the extranucleolar nucleoplasm constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner. Upon globally reducing RNA polymerase II transcription, the nuclear bodies enlarge and decrease in number. They occur closely adjacent to nuclear speckles or IGCs (interchromatin granule clusters) but coincide with TIDRs (transcription-inactivation-dependent RNA domains).
组织表达： Bone marrow,Brain,Colon,Epithelium,Fetal brain,Human endometrium,Liver,Lung
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