功能： function:UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.,polymorphism:The Thr-64 polymorphism is associated with an increased waist-to-hip ratio. The Leu-229 polymorphism is associated with susceptibility to type II diabetes mellitus.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,subunit:Acts as a dimer forming a proton channel.,tissue specificity:Brown adipose tissue.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Mitochondrion inner membrane ; Multi-pass membrane protein .
组织表达： Brown adipose tissue.
科研货号： PLA008683
UCP1 Polyclonal Antibody
Catalog NoPLA008683
Product information
基因名称： UCP1 SLC25A7 UCP
蛋白名称： Mitochondrial brown fat uncoupling protein 1 (UCP 1) (Solute carrier family 25 member 7) (Thermogenin)
功能： function:UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.,polymorphism:The Thr-64 polymorphism is associated with an increased waist-to-hip ratio. The Leu-229 polymorphism is associated with susceptibility to type II diabetes mellitus.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,subunit:Acts as a dimer forming a proton channel.,tissue specificity:Brown adipose tissue.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Mitochondrion inner membrane ; Multi-pass membrane protein .
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