功能: function:Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection.,induction:By phorbol ester and inflammatory cytokines, such as TNF-alpha, or IL-1-beta, but not by growth factors.,similarity:Belongs to the Bcl-2 family.,subunit:Interacts directly with BAK1, BID, BMF and BBC3 (By similarity). Interacts directly with BCL2L11/BIM. Interacts with BAX isoform Sigma.,tissue specificity:Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm .
组织表达: Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.
科研货号: PLA008673
B2LA1 Polyclonal Antibody
Catalog NoPLA008673
Product information
基因名称: BCL2A1 BCL2L5 BFL1 GRS HBPA1
蛋白名称: Bcl-2-related protein A1 (Bcl-2-like protein 5) (Bcl2-L-5) (Hemopoietic-specific early response protein) (Protein BFL-1) (Protein GRS)
功能: function:Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection.,induction:By phorbol ester and inflammatory cytokines, such as TNF-alpha, or IL-1-beta, but not by growth factors.,similarity:Belongs to the Bcl-2 family.,subunit:Interacts directly with BAK1, BID, BMF and BBC3 (By similarity). Interacts directly with BCL2L11/BIM. Interacts with BAX isoform Sigma.,tissue specificity:Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm .
组织表达: Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.