功能: function:Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.,PTM:Phosphorylation probably regulates the interaction with NSH2.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Predominantly located at podocyte slit diaphragm.,subunit:Interacts with NPHS1/nephrin, TJP1/ZO-1 and C-terminus of NPHS2/podocin.,tissue specificity:Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type I membrane protein . Predominantly located at podocyte slit diaphragm.
组织表达: Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.
科研货号: PLA008628
KIRR1 Polyclonal Antibody
Catalog NoPLA008628
Product information
基因名称: KIRREL KIRREL1 NEPH1
蛋白名称: Kin of IRRE-like protein 1 (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1)
功能: function:Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.,PTM:Phosphorylation probably regulates the interaction with NSH2.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Predominantly located at podocyte slit diaphragm.,subunit:Interacts with NPHS1/nephrin, TJP1/ZO-1 and C-terminus of NPHS2/podocin.,tissue specificity:Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type I membrane protein . Predominantly located at podocyte slit diaphragm.
组织表达: Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.