功能： function:May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,subcellular location:Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Multi-pass membrane protein . Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
组织表达： Liver,
科研货号： PLA008379
MRGRD Polyclonal Antibody
Catalog NoPLA008379
Product information
基因名称： MRGPRD MRGD
蛋白名称： Mas-related G-protein coupled receptor member D (Beta-alanine receptor) (G-protein coupled receptor TGR7)
功能： function:May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,subcellular location:Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Multi-pass membrane protein . Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
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