功能： function:Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.,PTM:Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane; Multi-pass membrane protein.
组织表达： Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
功能： function:Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.,PTM:Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane; Multi-pass membrane protein.
组织表达： Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
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