功能： disease:Defects in SALL4 are the cause of Duane-radial ray syndrome (DRRS) [MIM:607323]; also known as Okihiro syndrome. DRRS is a disorder characterized by the association of forearm malformations with Duane retraction syndrome.,disease:Defects in SALL4 are the cause of IVIC syndrome [MIM:147750]. IVIC syndrome is an autosomal dominant condition characterized by upper limbs anomalies (radial ray defects, carpal bones fusion), extraocular motor disturbances, congenital bilateral non-progressive mixed hearing loss. Other less consistent malformations include heart involvement, mild thrombocytopenia and leukocytosis (before age 50), shoulder girdle hypoplasia, imperforate anus, kidney malrotation or rectovaginal fistula. The IVIC syndrome is an allelic disorder of Duane-radial ray syndrome (DRRS) with a similar phenotype.,function:Probable transcription factor.,similarity:Belongs to the sal C2H2-type zinc-finger protein family.,similarity:Contains 7 C2H2-type zinc fingers.,subunit:Interacts with NANOG.,tissue specificity:Expressed in testis.,
相关产品： YN2448,YM6670,RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm. Nucleus.
组织表达： Expressed in testis. Constitutively expressed in acute myeloid leukemia (AML).
科研货号： PLA008266
SALL4 Polyclonal Antibody
Catalog NoPLA008266
Product information
基因名称： SALL4 ZNF797
蛋白名称： Sal-like protein 4 (Zinc finger protein 797) (Zinc finger protein SALL4)
功能： disease:Defects in SALL4 are the cause of Duane-radial ray syndrome (DRRS) [MIM:607323]; also known as Okihiro syndrome. DRRS is a disorder characterized by the association of forearm malformations with Duane retraction syndrome.,disease:Defects in SALL4 are the cause of IVIC syndrome [MIM:147750]. IVIC syndrome is an autosomal dominant condition characterized by upper limbs anomalies (radial ray defects, carpal bones fusion), extraocular motor disturbances, congenital bilateral non-progressive mixed hearing loss. Other less consistent malformations include heart involvement, mild thrombocytopenia and leukocytosis (before age 50), shoulder girdle hypoplasia, imperforate anus, kidney malrotation or rectovaginal fistula. The IVIC syndrome is an allelic disorder of Duane-radial ray syndrome (DRRS) with a similar phenotype.,function:Probable transcription factor.,similarity:Belongs to the sal C2H2-type zinc-finger protein family.,similarity:Contains 7 C2H2-type zinc fingers.,subunit:Interacts with NANOG.,tissue specificity:Expressed in testis.,
相关产品： YN2448,YM6670,RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm. Nucleus.
组织表达： Expressed in testis. Constitutively expressed in acute myeloid leukemia (AML).
在线咨询
湘公网安备