功能： function:Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.,similarity:Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.,subunit:Homotetramer, which consists of two pairs of disulfide-linked chains.,tissue specificity:Plasma. Prominent constituent of late-pregnancy sera.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted.
组织表达： Plasma. Prominent constituent of late-pregnancy sera.
科研货号： PLA008265
PZP Polyclonal Antibody
Catalog NoPLA008265
Product information
基因名称： PZP CPAMD6
蛋白名称： Pregnancy zone protein (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6)
功能： function:Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.,similarity:Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.,subunit:Homotetramer, which consists of two pairs of disulfide-linked chains.,tissue specificity:Plasma. Prominent constituent of late-pregnancy sera.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted.
组织表达： Plasma. Prominent constituent of late-pregnancy sera.
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