功能: function:Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.,induction:Up-regulated by IL-1alpha and prostaglandin E2 in cultured osteogenic sarcoma cells.,online information:LLT1,similarity:Contains 1 C-type lectin domain.,tissue specificity:Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type II membrane protein .; [Isoform 2]: Endoplasmic reticulum .; [Isoform 4]: Endoplasmic reticulum .
组织表达: Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells.
科研货号: PLA008234
CLC2D Polyclonal Antibody
Catalog NoPLA008234
Product information
基因名称: CLEC2D CLAX LLT1 OCIL
蛋白名称: C-type lectin domain family 2 member D (Lectin-like NK cell receptor) (Lectin-like transcript 1) (LLT-1) (Osteoclast inhibitory lectin)
功能: function:Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.,induction:Up-regulated by IL-1alpha and prostaglandin E2 in cultured osteogenic sarcoma cells.,online information:LLT1,similarity:Contains 1 C-type lectin domain.,tissue specificity:Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type II membrane protein .; [Isoform 2]: Endoplasmic reticulum .; [Isoform 4]: Endoplasmic reticulum .
组织表达: Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells.