蛋白名称: Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1)
功能: domain:Binds to membranes enriched in PtdIns3,4P2 via the C-terminal PH domain.,function:Binds specifically to phosphatidylinositol-3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane.,similarity:Contains 1 PH domain.,similarity:Contains 2 PH domains.,subcellular location:Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2.,subunit:Binds MPDZ and PTPN13.,tissue specificity:Highly expressed in skeletal muscle, thymus, pancreas, placenta and lung. Detected at low levels in brain, heart, peripheral blood leukocytes, testis, ovary, spinal cord, thyroid, kidney, liver, small intestine and colon.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm . Cell membrane ; Peripheral membrane protein. Nucleus . Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2. .
组织表达: Highly expressed in skeletal muscle, thymus, pancreas, placenta and lung. Detected at low levels in brain, heart, peripheral blood leukocytes, testis, ovary, spinal cord, thyroid, kidney, liver, small intestine and colon.
科研货号: PLA008233
PKHA1 Polyclonal Antibody
Catalog NoPLA008233
Product information
基因名称: PLEKHA1 TAPP1
蛋白名称: Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1)
功能: domain:Binds to membranes enriched in PtdIns3,4P2 via the C-terminal PH domain.,function:Binds specifically to phosphatidylinositol-3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane.,similarity:Contains 1 PH domain.,similarity:Contains 2 PH domains.,subcellular location:Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2.,subunit:Binds MPDZ and PTPN13.,tissue specificity:Highly expressed in skeletal muscle, thymus, pancreas, placenta and lung. Detected at low levels in brain, heart, peripheral blood leukocytes, testis, ovary, spinal cord, thyroid, kidney, liver, small intestine and colon.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm . Cell membrane ; Peripheral membrane protein. Nucleus . Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2. .
组织表达: Highly expressed in skeletal muscle, thymus, pancreas, placenta and lung. Detected at low levels in brain, heart, peripheral blood leukocytes, testis, ovary, spinal cord, thyroid, kidney, liver, small intestine and colon.