功能： disease:A chromosomal aberration involving LMO2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p13;q11) with TCRD.,domain:The second LIM zinc-binding domain interacts with KDM5A.,function:Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.,similarity:Contains 2 LIM zinc-binding domains.,subunit:Interacts via its LIM domains with ELF2 and LBD1. Also interacts with basic helix-loop-helix protein TAL1/SCL and can assemble in a complex with LMO2 and TAL1/SCL (By similarity). Interacts with BEX2 and KDM5A.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus .
组织表达： Brain,Colon,Kidney,
科研货号： PLA008108
RBTN2 Polyclonal Antibody
Catalog NoPLA008108
Product information
基因名称： LMO2 RBTN2 RBTNL1 RHOM2 TTG2
蛋白名称： Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)
功能： disease:A chromosomal aberration involving LMO2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p13;q11) with TCRD.,domain:The second LIM zinc-binding domain interacts with KDM5A.,function:Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.,similarity:Contains 2 LIM zinc-binding domains.,subunit:Interacts via its LIM domains with ELF2 and LBD1. Also interacts with basic helix-loop-helix protein TAL1/SCL and can assemble in a complex with LMO2 and TAL1/SCL (By similarity). Interacts with BEX2 and KDM5A.,
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