功能: function:Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.,PTM:N-glycosylated.,similarity:Contains 3 TNFR-Cys repeats.,subunit:Interacts with TRAF2, TRAF3 and TRAF5.,tissue specificity:Widely expressed, with the highest expression in lung, spleen and thymus.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type I membrane protein .
组织表达: Widely expressed, with the highest expression in lung, spleen and thymus. Expressed in a subpopulation of B cells and monocytes (PubMed:18193050). Expressed in naive T cells (PubMed:19915044).
科研货号: PLA008107
TNR14 Polyclonal Antibody
Catalog NoPLA008107
Product information
基因名称: TNFRSF14 HVEA HVEM UNQ329/PRO509
蛋白名称: Tumor necrosis factor receptor superfamily member 14 (Herpes virus entry mediator A) (Herpesvirus entry mediator A) (HveA) (Tumor necrosis factor receptor-like 2) (TR2) (CD antigen CD270)
功能: function:Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.,PTM:N-glycosylated.,similarity:Contains 3 TNFR-Cys repeats.,subunit:Interacts with TRAF2, TRAF3 and TRAF5.,tissue specificity:Widely expressed, with the highest expression in lung, spleen and thymus.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type I membrane protein .
组织表达: Widely expressed, with the highest expression in lung, spleen and thymus. Expressed in a subpopulation of B cells and monocytes (PubMed:18193050). Expressed in naive T cells (PubMed:19915044).