细胞定位: Golgi apparatus membrane ; Single-pass type II membrane protein . A small fraction may also be present at the cell surface, where it acts as a B-cell receptor.
组织表达: Expressed in B-cell-enriched tissues but not in fetal or adult thymus. Expressed in fetal and adult spleen, lymph node, tonsil, bone marrow and peripheral leukocytes. Not expressed in T-cells. In pro-B, pre-B, and mature B-cell lines, it colocalizes with RAG1.
细胞定位: Golgi apparatus membrane ; Single-pass type II membrane protein . A small fraction may also be present at the cell surface, where it acts as a B-cell receptor.
组织表达: Expressed in B-cell-enriched tissues but not in fetal or adult thymus. Expressed in fetal and adult spleen, lymph node, tonsil, bone marrow and peripheral leukocytes. Not expressed in T-cells. In pro-B, pre-B, and mature B-cell lines, it colocalizes with RAG1.