功能： cell activation, activation of innate immune response, innate immune response activating cell surface receptor signaling pathway, stimulatory C-type lectin receptor signaling pathway, immune effector process, activation of immune response, response to tumor cell, immune response to tumor cell, immune response-activating cell surface receptor signaling pathway, antigen processing and presentation of peptide antigen via MHC class I, positive regulation of immune system process, immune response-activating signal transduction, innate immune response-activating signal transduction, immune response-regulating signal transduction, immune response-regulating cell surface receptor signaling pathway, defense response, immune response, response to DNA damage stimulus, cell surface receptor linked signal transduction, cell death, response to temperature stimulus, response to heat, response to virus, response to bacterium, response to abiotic stimulus, death, cytolysis, antigen processing and presentation,positive regulation of defense response, cellular response to stress, T cell activation, defense response to bacterium,regulation of innate immune response, positive regulation of innate immune response, leukocyte activation, gamma-delta T cell activation, lymphocyte activation, antigen processing and presentation of peptide antigen, positive regulation of response to stimulus, positive regulation of immune response, defense response to virus,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Expressed on the cell surface in gastric epithelium, endothelial cells and fibroblasts and in the cytoplasm in keratinocytes and monocytes. Infection with human adenovirus 5 suppresses cell surface expression due to the adenoviral E3-19K protein which causes retention in the endoplasmic reticulum. .
组织表达： Widely expressed with the exception of the central nervous system where it is absent. Expressed predominantly in gastric epithelium and also in monocytes, keratinocytes, endothelial cells, fibroblasts and in the outer layer of Hassal's corpuscles within the medulla of normal thymus. In skin, expressed mainly in the keratin layers, basal cells, ducts and follicles. Also expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In thyomas, overexpressed in cortical and medullar epithelial cells. Tumors expressing MICA display increased levels of gamma delta T-cells.
科研货号： PLA008055
MICA Polyclonal Antibody
Catalog NoPLA008055
Product information
基因名称： MICA PERB11.1
蛋白名称： MHC class I polypeptide-related sequence A (MIC-A)
功能： cell activation, activation of innate immune response, innate immune response activating cell surface receptor signaling pathway, stimulatory C-type lectin receptor signaling pathway, immune effector process, activation of immune response, response to tumor cell, immune response to tumor cell, immune response-activating cell surface receptor signaling pathway, antigen processing and presentation of peptide antigen via MHC class I, positive regulation of immune system process, immune response-activating signal transduction, innate immune response-activating signal transduction, immune response-regulating signal transduction, immune response-regulating cell surface receptor signaling pathway, defense response, immune response, response to DNA damage stimulus, cell surface receptor linked signal transduction, cell death, response to temperature stimulus, response to heat, response to virus, response to bacterium, response to abiotic stimulus, death, cytolysis, antigen processing and presentation,positive regulation of defense response, cellular response to stress, T cell activation, defense response to bacterium,regulation of innate immune response, positive regulation of innate immune response, leukocyte activation, gamma-delta T cell activation, lymphocyte activation, antigen processing and presentation of peptide antigen, positive regulation of response to stimulus, positive regulation of immune response, defense response to virus,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Expressed on the cell surface in gastric epithelium, endothelial cells and fibroblasts and in the cytoplasm in keratinocytes and monocytes. Infection with human adenovirus 5 suppresses cell surface expression due to the adenoviral E3-19K protein which causes retention in the endoplasmic reticulum. .
组织表达： Widely expressed with the exception of the central nervous system where it is absent. Expressed predominantly in gastric epithelium and also in monocytes, keratinocytes, endothelial cells, fibroblasts and in the outer layer of Hassal's corpuscles within the medulla of normal thymus. In skin, expressed mainly in the keratin layers, basal cells, ducts and follicles. Also expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In thyomas, overexpressed in cortical and medullar epithelial cells. Tumors expressing MICA display increased levels of gamma delta T-cells.
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