功能: function:Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets.,online information:CLEC-2,PTM:Glycosylated.,PTM:Phosphorylated on tyrosine residue in response to rhodocytin binding.,similarity:Contains 1 C-type lectin domain.,subunit:Monomer.,tissue specificity:Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Membrane ; Single-pass type II membrane protein .
组织表达: Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.
科研货号: PLA008013
CLC1B Polyclonal Antibody
Catalog NoPLA008013
Product information
基因名称: CLEC1B CLEC2 UNQ721/PRO1384
蛋白名称: C-type lectin domain family 1 member B (C-type lectin-like receptor 2) (CLEC-2)
功能: function:Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets.,online information:CLEC-2,PTM:Glycosylated.,PTM:Phosphorylated on tyrosine residue in response to rhodocytin binding.,similarity:Contains 1 C-type lectin domain.,subunit:Monomer.,tissue specificity:Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Membrane ; Single-pass type II membrane protein .
组织表达: Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.